Life Science Buffers

Balanced salt solutions and powders used for molecular, protein, nucleic acid, and cell biology applications including cell culture, electrophoresis, ELISA, and chromatography processes; available in a variety of formulations and grades.

Buffer solutions serve to keep pH (acidity or alkalinity) nearly constant in a variety of chemical and biological applications. For example, a bicarbonate buffer helps maintain the pH of blood, a buffered saline maintains cellular contents at a consistent pH level, and buffers help maintain a narrow pH range for enzymes to function correctly.

Most biological samples used in research are kept at a pH of about 7.4. Common biological buffers used for tissue culture include Dulbeccos phosphate buffered saline (PBS), Tris base, HEPES, MOPS, PIPES, and other formulations developed for specific cell lines or applications. Most buffers used in cell culture are also DNase-, RNase-, and protease-free.

The choice of buffer for a particular biological reaction or site depends on several factors:

Temperature
Desired or target pH
Buffer toxicity (to the system)
Buffer interactions with other system components

Search Within Results

286 – 300 of 3,503 results

286

BES-buffered saline (2X), low endotoxin, Thermo Scientific™

Pricing & Availability
Specifications

Name Note	low endotoxin
Storage Note 1	2° to 8°C
Color	Colorless
Physical Form	Liquid
Chemical Name or Material	BES-buffered saline (2X)
TSCA	No
Recommended Storage	Keep cold

287

Enzyme storage buffer in PBS and glycerol, autoclaved, Thermo Scientific™

For frozen storage of enzymes

Pricing & Availability
Specifications

Physical Form	Liquid
Chemical Name or Material	Enzyme storage buffer in PBS and glycerol
Recommended Storage	Ambient temperatures

288

POPSO, 0.2M buffer soln., pH 8.0, Thermo Scientific™

CAS: 108321-07-9 Molecular Formula: C10H20N2Na2O8S2 Molecular Weight (g/mol): 406.376 MDL Number: MFCD00070005 InChI Key: XMRCLLXGMGEVHS-UHFFFAOYSA-L PubChem CID: 53393457 IUPAC Name: disodium;2-hydroxy-3-[4-(2-hydroxy-3-sulfonatopropyl)piperazin-1-yl]propane-1-sulfonate SMILES: C1CN(CCN1CC(CS(=O)(=O)[O-])O)CC(CS(=O)(=O)[O-])O.[Na+].[Na+]

Pricing & Availability
Specifications

PubChem CID	53393457
CAS	108321-07-9
Molecular Weight (g/mol)	406.376
MDL Number	MFCD00070005
SMILES	C1CN(CCN1CC(CS(=O)(=O)[O-])O)CC(CS(=O)(=O)[O-])O.[Na+].[Na+]
IUPAC Name	disodium;2-hydroxy-3-[4-(2-hydroxy-3-sulfonatopropyl)piperazin-1-yl]propane-1-sulfonate
InChI Key	XMRCLLXGMGEVHS-UHFFFAOYSA-L
Molecular Formula	C10H20N2Na2O8S2

289

Thermo Scientific Chemicals PIPES, 0.5M buffer soln., pH 8.0

CAS: 5625-37-6 Molecular Formula: C8H18N2O6S2 Molecular Weight (g/mol): 302.36 MDL Number: MFCD00006159 InChI Key: IHPYMWDTONKSCO-UHFFFAOYSA-N PubChem CID: 79723 ChEBI: CHEBI:44933 IUPAC Name: 2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonic acid SMILES: C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)O

Pricing & Availability
Specifications

PubChem CID	79723
CAS	5625-37-6
Molecular Weight (g/mol)	302.36
ChEBI	CHEBI:44933
MDL Number	MFCD00006159
SMILES	C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)O
IUPAC Name	2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonic acid
InChI Key	IHPYMWDTONKSCO-UHFFFAOYSA-N
Molecular Formula	C8H18N2O6S2

290

Promotions Available

MOPS Hemisodium Salt, Biological Buffer, Spectrum™ Chemical

CAS: 117961-20-3 Molecular Formula: C14H29N2NaO8S2 Molecular Weight (g/mol): 440.50 InChI Key: OVCWZKQPQOVIDT-UHFFFAOYSA-M IUPAC Name: sodium 3-(morpholin-4-yl)propane-1-sulfonic acid 3-(morpholin-4-yl)propane-1-sulfonate SMILES: [Na+].OS(=O)(=O)CCCN1CCOCC1.[O-]S(=O)(=O)CCCN1CCOCC1

Pricing & Availability
Specifications

CAS	117961-20-3
Molecular Weight (g/mol)	440.50
SMILES	[Na+].OS(=O)(=O)CCCN1CCOCC1.[O-]S(=O)(=O)CCCN1CCOCC1
IUPAC Name	sodium 3-(morpholin-4-yl)propane-1-sulfonic acid 3-(morpholin-4-yl)propane-1-sulfonate
InChI Key	OVCWZKQPQOVIDT-UHFFFAOYSA-M
Molecular Formula	C14H29N2NaO8S2

291

bis-Tris, ≥99%, MP Biomedicals™

CAS: 6976-37-0 Molecular Formula: C8H19NO5 Molecular Weight (g/mol): 209.242 InChI Key: OWMVSZAMULFTJU-UHFFFAOYSA-N PubChem CID: 81462 ChEBI: CHEBI:41250 IUPAC Name: 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol SMILES: C(CO)N(CCO)C(CO)(CO)CO

Pricing & Availability
Specifications

PubChem CID	81462
CAS	6976-37-0
Molecular Weight (g/mol)	209.242
ChEBI	CHEBI:41250
SMILES	C(CO)N(CCO)C(CO)(CO)CO
IUPAC Name	2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol
InChI Key	OWMVSZAMULFTJU-UHFFFAOYSA-N
Molecular Formula	C8H19NO5

292

MilliporeSigma™ Calbiochem™ OmniPur™ PBS Tablets

Makes 1X solution when dissolved in 100mL distilled or deionized water from each tablet.

Pricing & Availability

293

Promotions Available

ACES, Biological Buffer, 98%, Spectrum™ Chemical

Pricing & Availability

294

Thermo Scientific Chemicals Tris(hydroxymethyl)aminomethane, Electrophoresis Grade, 99.5%

CAS: 77-86-1 Molecular Formula: C4H11NO3 Molecular Weight (g/mol): 121.136 MDL Number: MFCD00004679 InChI Key: LENZDBCJOHFCAS-UHFFFAOYSA-N Synonym: TRIS PubChem CID: 6503 ChEBI: CHEBI:9754 IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol SMILES: C(C(CO)(CO)N)O

Pricing & Availability
Specifications

PubChem CID	6503
CAS	77-86-1
Molecular Weight (g/mol)	121.136
ChEBI	CHEBI:9754
MDL Number	MFCD00004679
SMILES	C(C(CO)(CO)N)O
Synonym	TRIS
IUPAC Name	2-amino-2-(hydroxymethyl)propane-1,3-diol
InChI Key	LENZDBCJOHFCAS-UHFFFAOYSA-N
Molecular Formula	C4H11NO3

295

ADA, 0.2M buffer soln., pH 7.5, Thermo Scientific™

CAS: 7415-22-7 Molecular Formula: C6H9N2NaO5 Molecular Weight (g/mol): 212.137 MDL Number: MFCD00065483 InChI Key: QCGKKVWCABJQQI-UHFFFAOYSA-M PubChem CID: 23679048 IUPAC Name: sodium;2-[(2-amino-2-oxoethyl)-(carboxymethyl)amino]acetate SMILES: C(C(=O)N)N(CC(=O)O)CC(=O)[O-].[Na+]

Pricing & Availability
Specifications

PubChem CID	23679048
CAS	7415-22-7
Molecular Weight (g/mol)	212.137
MDL Number	MFCD00065483
SMILES	C(C(=O)N)N(CC(=O)O)CC(=O)[O-].[Na+]
IUPAC Name	sodium;2-[(2-amino-2-oxoethyl)-(carboxymethyl)amino]acetate
InChI Key	QCGKKVWCABJQQI-UHFFFAOYSA-M
Molecular Formula	C6H9N2NaO5

296

HEPPSO, 99%, MP Biomedicals

CAS: 68399-78-0 Molecular Formula: C9H20N2O5S Molecular Weight (g/mol): 268.328 InChI Key: GIZQLVPDAOBAFN-UHFFFAOYSA-N Synonym: heppso,2-hydroxy-3-4-2-hydroxyethyl piperazin-1-yl propane-1-sulfonic acid,n-hydroxyethyl piperazine-n'-2-hydroxypropanesulfonic acid,beta-hydroxy-4-2-hydroxyethyl piperazine-1-propanesulphonic acid,beta-hydroxy-4-2-hydroxyethyl-1-piperazinepropanesulfonic acid,3-4-2-hydroxyethyl-1-piperazinyl-2-hydroxypropanesulfonic acid,4-2-hydroxyethyl piperazine-1-2-hydroxypropane-3-sulfonic acid,4-2-hydroxyethyl piperazine-1-2-hydroxypropane sulfonic acid free acid,2-hydroxy-3-4-2-hydroxyethyl piperazinyl propanesulfonic acid PubChem CID: 100205 ChEBI: CHEBI:32951 IUPAC Name: 2-hydroxy-3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid SMILES: C1CN(CCN1CCO)CC(CS(=O)(=O)O)O

Pricing & Availability
Specifications

PubChem CID	100205
CAS	68399-78-0
Molecular Weight (g/mol)	268.328
ChEBI	CHEBI:32951
SMILES	C1CN(CCN1CCO)CC(CS(=O)(=O)O)O
Synonym	heppso,2-hydroxy-3-4-2-hydroxyethyl piperazin-1-yl propane-1-sulfonic acid,n-hydroxyethyl piperazine-n'-2-hydroxypropanesulfonic acid,beta-hydroxy-4-2-hydroxyethyl piperazine-1-propanesulphonic acid,beta-hydroxy-4-2-hydroxyethyl-1-piperazinepropanesulfonic acid,3-4-2-hydroxyethyl-1-piperazinyl-2-hydroxypropanesulfonic acid,4-2-hydroxyethyl piperazine-1-2-hydroxypropane-3-sulfonic acid,4-2-hydroxyethyl piperazine-1-2-hydroxypropane sulfonic acid free acid,2-hydroxy-3-4-2-hydroxyethyl piperazinyl propanesulfonic acid
IUPAC Name	2-hydroxy-3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid
InChI Key	GIZQLVPDAOBAFN-UHFFFAOYSA-N
Molecular Formula	C9H20N2O5S

297

Promotions Available

Thermo Scientific Chemicals ACES, 99+%, for biochemistry

CAS: 7365-82-4 Molecular Formula: C4H10N2O4S Molecular Weight (g/mol): 182.194 MDL Number: MFCD00008030 InChI Key: DBXNUXBLKRLWFA-UHFFFAOYSA-N Synonym: N-(2-Acetamido)-2-aminoethanesulfonic acid,N-(Carbamoylmethyl)taurine PubChem CID: 81832 ChEBI: CHEBI:39062 IUPAC Name: 2-[(2-amino-2-oxoethyl)amino]ethanesulfonic acid SMILES: C(CS(=O)(=O)O)NCC(=O)N

Pricing & Availability
Specifications

PubChem CID	81832
CAS	7365-82-4
Molecular Weight (g/mol)	182.194
ChEBI	CHEBI:39062
MDL Number	MFCD00008030
SMILES	C(CS(=O)(=O)O)NCC(=O)N
Synonym	N-(2-Acetamido)-2-aminoethanesulfonic acid,N-(Carbamoylmethyl)taurine
IUPAC Name	2-[(2-amino-2-oxoethyl)amino]ethanesulfonic acid
InChI Key	DBXNUXBLKRLWFA-UHFFFAOYSA-N
Molecular Formula	C4H10N2O4S

298

Promotions Available

Thermo Scientific Chemicals Tris Borate EDTA buffer, for molecular biology, 10x, DNAse, RNAse and Protease free, pH 8.3

CAS: 610769-35-2 Molecular Formula: C14H30BN3O14 Molecular Weight (g/mol): 475.211 MDL Number: MFCD00236358 InChI Key: OSBLTNPMIGYQGY-UHFFFAOYSA-N Synonym: 2-Amino-2-(hydroxymethyl)-1, 3-propanediol,TRIS,Tris buffer,Tromethamine,Tromethane PubChem CID: 21257725 IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol;2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid;boric acid SMILES: B(O)(O)O.C(CN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O.C(C(CO)(CO)N)O

Pricing & Availability
Specifications

PubChem CID	21257725
CAS	610769-35-2
Molecular Weight (g/mol)	475.211
MDL Number	MFCD00236358
SMILES	B(O)(O)O.C(CN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O.C(C(CO)(CO)N)O
Synonym	2-Amino-2-(hydroxymethyl)-1, 3-propanediol,TRIS,Tris buffer,Tromethamine,Tromethane
IUPAC Name	2-amino-2-(hydroxymethyl)propane-1,3-diol;2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid;boric acid
InChI Key	OSBLTNPMIGYQGY-UHFFFAOYSA-N
Molecular Formula	C14H30BN3O14

299

MP Biomedicals™ 1X Hanks' Balanced Salt Solution (Modified) without Magnesium and Calcium

Minimize cell attachment or aggregation.

Pricing & Availability

300

Physical Form	Liquid
pH	7.2 to 7.5
Chemical Name or Material	HEPES solution
Concentration	1 M
Solution Type	Buffer

Life Science Buffers

Filtered Search Results

Narrow Results